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Hongsuk Suh Selected Research

Chenodeoxycholic Acid (Chenix)

5/2009Efficacy on anaplastic thyroid carcinoma of valproic acid alone or in combination with doxorubicin, a synthetic chenodeoxycholic acid derivative, or lactacystin.
10/2008A chenodeoxycholic derivative, HS-1200, induces apoptosis and cell cycle modulation via Egr-1 gene expression control on human hepatoma cells.
4/2007A novel chenodeoxycholic derivative HS-1200 enhances radiation-induced apoptosis in MCF-7 cells.
11/2005Synthetic bile acid derivatives induce apoptosis through a c-Jun N-terminal kinase and NF-kappaB-dependent process in human cervical carcinoma cells.
9/2005Synthetic chenodeoxycholic acid derivatives inhibit glioblastoma multiform tumor growth in vitro and in vivo.
7/2004Synthetic bile acid derivatives inhibit cell proliferation and induce apoptosis in HT-29 human colon cancer cells.
12/2003Orphan nuclear receptor Nur77 translocates to mitochondria in the early phase of apoptosis induced by synthetic chenodeoxycholic acid derivatives in human stomach cancer cell line SNU-1.
9/2003Apoptosis and modulation of cell cycle control by synthetic derivatives of ursodeoxycholic acid and chenodeoxycholic acid in human prostate cancer cells.
3/2003Synthetic chenodeoxycholic acid derivative HS-1200-induced apoptosis of p815 mastocytoma cells is augmented by co-treatment with lactacystin.

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Hongsuk Suh Research Topics

Disease

18Neoplasms (Cancer)
08/2017 - 09/2003
6Breast Neoplasms (Breast Cancer)
08/2017 - 11/2005
5Carcinoma (Carcinomatosis)
05/2013 - 09/2003
3Colonic Neoplasms (Colon Cancer)
01/2017 - 07/2004
2Hypoxia (Hypoxemia)
08/2017 - 07/2013
2Prostatic Neoplasms (Prostate Cancer)
06/2011 - 09/2003
2Experimental Melanoma
08/2010 - 02/2009
1Phototoxic Dermatitis (Phototoxicity)
01/2016
1Burns
12/2014
1Mitochondrial Diseases (Mitochondrial Disease)
07/2013
1Polyploidy
06/2011
1Carcinogenesis
04/2010
1Kidney Neoplasms (Kidney Cancer)
12/2009
1Anaplastic Thyroid Carcinoma
05/2009
1Hepatocellular Carcinoma (Hepatoma)
10/2008
1Atherosclerosis
12/2007
1Melanoma (Melanoma, Malignant)
09/2007
1Glioblastoma (Glioblastoma Multiforme)
09/2005
1Stomach Neoplasms (Stomach Cancer)
12/2003
1Mastocytoma
03/2003

Drug/Important Bio-Agent (IBA)

10ResveratrolIBA
08/2017 - 04/2009
104-(6-hydroxy-2-naphthyl)-1,3-benzenediolIBA
08/2017 - 04/2009
9Chenodeoxycholic Acid (Chenix)FDA Link
05/2009 - 03/2003
8HS 1200IBA
10/2008 - 03/2003
5HS-1199IBA
11/2005 - 09/2003
3Doxorubicin (Adriamycin)FDA LinkGeneric
05/2014 - 05/2009
3polyhistidineIBA
05/2014 - 01/2012
3Melanins (Melanin)IBA
08/2010 - 09/2007
3HS 1183IBA
11/2005 - 09/2003
3Bile Acids and Salts (Bile Acids)IBA
11/2005 - 09/2003
3Ursodeoxycholic Acid (Urso)FDA LinkGeneric
11/2005 - 09/2003
2Therapeutic UsesIBA
08/2017 - 01/2017
2Proteins (Proteins, Gene)FDA Link
08/2017 - 04/2010
2PolymersIBA
12/2014 - 05/2013
2MicellesIBA
05/2014 - 05/2013
2Pharmaceutical PreparationsIBA
05/2014 - 05/2013
2Drug CarriersIBA
03/2014 - 05/2013
2lactacystinIBA
05/2009 - 03/2003
1Antineoplastic Agents (Antineoplastics)IBA
08/2017
1Biomarkers (Surrogate Marker)IBA
08/2017
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2017
1Oxygen (Dioxygen)IBA
08/2017
1Histidine (L-Histidine)FDA Link
05/2014
1IR 820IBA
05/2014
1LipopeptidesIBA
05/2014
1Ethylene Glycol (Monoethylene Glycol)IBA
03/2014
1HydrogelsIBA
03/2014
1Dimethoate (Rogor)IBA
03/2014
1CalciumIBA
07/2013
1Reactive Oxygen Species (Oxygen Radicals)IBA
07/2013
1poly-N-isopropylacrylamideIBA
05/2013
1poly(N- isopropylacrylamide)- block- poly(histidine)IBA
05/2013
1InterferonsIBA
04/2012
1Indicators and Reagents (Reagents)IBA
04/2012
1Interleukin-4 (Interleukin 4)IBA
04/2012
1Concanavalin AIBA
04/2012
1Interleukin-2 (IL2)IBA
04/2012
1ProdrugsIBA
01/2012
1protoporphyrin IXIBA
01/2012
1AcidsIBA
01/2012
11-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2012
1CCAAT-Enhancer-Binding ProteinsIBA
04/2010
1Glucose (Dextrose)FDA LinkGeneric
04/2010
1Valproic Acid (Depakote)FDA LinkGeneric
05/2009
1Histone Deacetylases (Histone Deacetylase)IBA
05/2009
1Proteasome InhibitorsIBA
05/2009
1Monophenol Monooxygenase (Tyrosinase)IBA
02/2009
13- (4'- hydroxyl- 3',5'- dimethoxyphenyl)propionic acidIBA
12/2007
1hexamethylenebis(dimethyl- (3- phthalimidopropyl)ammonium bromide) (W 84)IBA
12/2007
1CholesterolIBA
12/2007
1AntioxidantsIBA
12/2007
1JNK Mitogen-Activated Protein KinasesIBA
11/2005
1NF-kappa B (NF-kB)IBA
11/2005
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
09/2005
1Cytochromes c (Cytochrome c)IBA
09/2005
1Proteasome Endopeptidase Complex (Proteasome)IBA
09/2005
1Caspase 3 (Caspase-3)IBA
09/2005
1HS 1030IBA
07/2004
1CaspasesIBA
12/2003
1Orphan Nuclear ReceptorsIBA
12/2003

Therapy/Procedure

6Therapeutics
05/2014 - 09/2003
2Photochemotherapy (Photodynamic Therapy)
01/2016 - 01/2012
2Precision Medicine
10/2015 - 05/2014
2Drug Therapy (Chemotherapy)
05/2013 - 04/2012
1Nanospheres
01/2016
1Immunotherapy
04/2012